What Is Resveratrol And What Is Its Role In Nutritional Supplementation?

MakeWell - resveratrol

This article is intended for customers from all countries other than Germany*

Living with a chronic health condition can be an uphill battle. Day-to-day activities such as cleaning, working, or taking care of oneself can all become difficult to accomplish. Certain chronic conditions are worse than others, but they all have one thing in common: they drastically lessen a person’s quality of life.

When taking medication for chronic conditions, it’s often hard to find something that works. No medication is a one-size-fits-all and people with the same illness can respond differently to the same course of treatment. What works for one may not for another because of different body processes, the efficacy of the medication, and the onset of unwanted side effects.

Resveratrol is a compound that has gained attention with the promise of treating many conditions. But what is resveratrol, exactly?

What is resveratrol?

Resveratrol is a natural polyphenol that can be found in a wide variety of plant species. Most notably, resveratrol is found in the skin and seeds of red grapes.

Resveratrol has been hailed as a promising addition to the treatment for things such as:

  • Heart disease
  • Cancer
  • Alzheimer’s
  • Diabetes
  • Gastrointestinal distress
  • Fungal diseases
  • Urinary tract infections
  • Arthritis
  • Oxidative stress
  • Chronic inflammation
  • Low oestrogen
  • Neurological deficits

These conditions vary in severity and in how they affect the overall health of the body. For some, promising studies on resveratrol are available, whereas for others we lack the data to support several claims.


MakeWell - heart health
Image by Giulia Bertelli on Unsplash: Resveratrol has shown to have excellent health benefits in the area of heart health. Wondering what foods contain resveratrol? You might have some sitting in your fridge.

What are the benefits of using resveratrol?

Depending on the specific condition, the benefits of using resveratrol will differ. In the case of chronic inflammation, resveratrol has the ability to reduce or inhibit the production of certain proteins or enzymes that drive inflammation.

One publication found that the most profound health effects of using resveratrol could be found in those with chronic heart conditions. Resveratrol preserved the function of cell compartments within the heart and induced healing on the ventricular artery.

That same publication mentioned other benefits of resveratrol, such as:

  • Reduced blood glucose levels in diabetic cases
  • Lowered body weight
  • Improved mitochondrial function caused by oxidative stress
  • Inhibition of the overgrowth of bad bacteria within the gut

Another publication claims resveratrol could have dramatic effects on both weight and the build-up of plaque and fats in major arteries, leading to the improvement of cholesterol, obesity and cardiovascular disease. The sirtuin system is said to be the leading cause of improvements in this category.

What are the different forms of resveratrol?

Resveratrol can be made up of two very specific isomers: cis and trans resveratrol. Trans resveratrol is the superior isomer, and is generally attributed to having a more stable and potent reaction when it comes to bioavailability. Cis resveratrol doesn’t have as much of an ability to inhibit proliferation of cells, such as cancer cells, thus it was found to be the lesser of the two forms.

What is the best source of resveratrol?

Since resveratrol is a naturally occurring phytoalexin polyphenol, it is found in many plants. These plants are not always edible, but you can find resveratrol in high concentrations in foods such as:

  • Berries (including cranberries/blueberries)
  • Grapes (grape seeds and skin)
  • Peanuts (including skin)
  • Polygonum cuspidatium (Japanese knotweed)

If it’s difficult to consume these foods, or you can’t in high amounts, there are a wide array of resveratrol nutritional supplement options to choose from.  Many companies have developed their own formulas. One well known and high quality ingredient is Veri-TeTM Resveratrol. It is completely free from harmful substances, but full of all the health benefits of trans-resveratrol.


MakeWell - red wine
Image by Kym Ellis on Unsplash: Turns out that a nightly glass of red wine could pack a health punch due to its high levels of resveratrol.


There are a range of different types of resveratrol supplementation products available to choose from, including:

  • Capsules
  • Tablets
  • Softgels
  • Liquid Shots
  • Powder sticks
  • Film strips
  • Chocolate
  • Chewing Gum
  • Serum
  • Creams
  • Cosmetics

The bottom line

Although more research is needed on the efficacy of resveratrol on healing at a cellular level, many of the current studies have shown that it is a potential powerhouse when it comes to treating a wide variety of conditions. It has shown to have a positive effect on the healthy function of mitochondria within the cells, which leads to a healthier you.

Featured image by Hari Nandakumar on Unsplash