Energy Plus
natural ingredients for an effective and supportive treatment of Lyme disease

OPC-Plus

Effective nutritional supplement to support the treatment of Lyme disease

Energy plus is a natural nutritional supplement for supportive treatment of Lyme disease with ingredients specifically selected on the basis of various scientific studies.

Energy plus, our nutritional supplement for supportive treatment of Lyme disease, contains lactobacteria, phosphatidylcholine, L-carnitine, coenzyme Q10, phosphatidylserine, NADH, L-tyrosine, L-arginine, Vitamin C and Vitamin B5.

Ingredients

Lactobacteria
It is no secret that our health and wellbeing starts in the intestines. The digestive system also plays a key role in treating chronic fatigue syndromes. Various scientific studies have proven that the intestinal flora of chronic fatigue patients is often disturbed and that they have a significantly reduced diversity of bacteria present in their digestive systems. In addition, chronic fatigue patients were shown to have fewer bacteria types with an anti-inflammatory function than the control persons without chronic fatigue issues.

studies on lactobacteria as an ingredient

Giloteaux, Ludovic, et al. "Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome." Microbiome 4.1 (2016): 30. Sullivan, Åsa, Carl E. Nord, and Birgitta Evengård. "Effect of supplement with lactic-acid producing bacteria on fatigue and physical activity in patients with chronic fatigue syndrome." Nutrition journal 8.1 (2009): 4. Logan, Alan C., A. Venket Rao, and Dinaz Irani. "Chronic fatigue syndrome: lactic acid bacteria may be of therapeutic value." Medical hypotheses 60.6 (2003): 915-923.
Phosphatidylcholine
Phosphatidylcholine belongs to a group of phospholipides, which are a key component in our cell membranes. Phosphatidylcholine produces choline. This is then converted in the body to form the neurotransmitter acetylcholine, which is needed for communication between individual regions of the brain and therefore for mental performance and concentration. It is also important for the transmission of stimuli to the muscles and the resulting physical performance levels.

Scientific studies on phosphatidylcholine as an ingredient

Ellithorpe, Rita R., R. Settineri, and Garth L. Nicolson. "Pilot study: reduction of fatigue by use of a dietary supplement containing glycophospholipids." J Am Nutraceut Assoc 6.1 (2003): 23-28. Houston, Mark. "Lipid Replacement Therapy with a glycophospholipid-antioxidant-vitamin formulation significantly reduces fatigue within one week." (2010). Xiaojian, Qin, Ma Tingjun, and Jia Changxi. "Anti-fatigue Effect of Soybean Lecithin [J]." Chinese Agricultural Science Bulletin 12 (2010): 012. Nicolson, Garth L., and Rita Ellithorpe. "Lipid replacement and antioxidant nutritional therapy for restoring mitochondrial function and reducing fatigue in chronic fatigue syndrome and other fatiguing illnesses." Journal of Chronic Fatigue Syndrome 13.1 (2006): 57-68.
L-carnitine
In recent years, L-carnitine has made a name for itself in the drinks, powders and bars available at gyms. Although it has never been proven, it is believed to help with weight loss. More importantly, L-carnitine plays a key role in our metabolism. Long-chain fatty acids dock onto the L-carnitine and are transported to the mitochondria, where they are then converted into energy (ATP).

Scientific studies on L-carnitine as an ingredient

Malaguarnera, Mariano, et al. "L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial." The American journal of clinical nutrition 86.6 (2007): 1738-1744. Plioplys, Audrius V., and Sigita Plioplys. "Amantadine and L-carnitine treatment of chronic fatigue syndrome." Neuropsychobiology 35.1 (1997): 16-23. Gramignano, Giulia, et al. "Efficacy of l-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapy." Nutrition 22.2 (2006): 136-145. Colombani, Paolo, et al. "Effects of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: a double-blind crossover field study." European journal of applied physiology and occupational physiology 73.5 (1996): 434-439.
Coenzyme Q10
Q10 is known to many people as an anti-aging substance present in many skin creams or shower gels. This is mainly due to its anti-oxidative properties, which protect the cells from damage by so-called "free radicals". More importantly than its anti-aging function, the coenzymeQ10 is essential in the last stage of the respiratory chain (the term given to the process of energy production). If there is a deficit in Q10, the mitochondria, the power engines of our cells, are unable to produce and supply us with enough ATP (energy).

Scientific studies on Q10 as an ingredient

Koroshetz, Walter J., et al. "Energy metabolism defects in Huntington's disease and effects of coenzyme Q10." Annals of neurology 41.2 (1997): 160-165. Overvad, Kim, et al. "Coenzyme Q10 in health and disease." European Journal of Clinical Nutrition 53.10 (1999): 764-770. Crane, Frederick L. "Biochemical functions of coenzyme Q10." Journal of the American College of Nutrition 20.6 (2001): 591-598. Matthews, Russell T., et al. "Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects." Proceedings of the National Academy of Sciences 95.15 (1998): 8892-8897. Greenberg, Steven, and William H. Frishman. "Co‐Enzyme Q10: A New Drug for Cardiovascular Disease." The Journal of Clinical Pharmacology 30.7 (1990): 596-608.
Phosphatidylserin
Both phosphatidylcholine and phosphatidylserine are so-called phospholipides, a substance produced mostly in the brain and the central nervous system. Multiple studies have shown the positive influence of phosphatidylserine on the cognitive performance. However, this substance can also enhance our physical performance. Furthermore, scientific studies confirm that phosphatidylserine reduces attention deficiency and mood swings.

Scientific studies on phosphatidylserine as an ingredient

Crook, Thomas H., et al. "Effects of phosphatidylserine in age‐associated memory impairment." Neurology 41.5 (1991): 644-649. Jäger, Ralf, et al. "The effect of phosphatidylserine on golf performance." Journal of the International Society of Sports Nutrition 4.1 (2007): 23. Hirayama, S., et al. "The effect of phosphatidylserine administration on memory and symptoms of attention‐deficit hyperactivity disorder: a randomised, double‐blind, placebo‐controlled clinical trial." Journal of human nutrition and dietetics27.s2 (2014): 284-291. Work, How Does Phosphatidylserine. "Increase Mental Performance and Reduce Stress in Adults and Children and Athletes."
NADH
NADH is the abbreviation for "nicotinamide adenine dinucleotide (NAD) + hydrogen (H). NADH is often known as coenzyme 1 as it considered to be the most important of them all. NADH is a decisive component for the last stage of cell respiration, the oxygen-dependent energy metabolism. If there is no enough NADH present, the mitochondria are unable to produce enough ATP (energy), which can result in mental and physical fatigue. In addition, NADH is a powerful antioxidant, which can protect the cells from damage, such as that caused by free radicals.

Scientific studies on NADH as an ingredient

Castro-Marrero, Jesús; Cordero, Mario D.; Segundo, María José u. a. (2015): „Does Oral Coenzyme Q 10 Plus NADH Supplementation Improve Fatigue and Biochemical Parameters in Chronic Fatigue Syndrome?“. In: Antioxidants & Redox Signaling. 22 (8), S. 679-685, DOI: 10.1089/ars.2014.6181 Forsyth, Linda M., et al. "Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome." Annals of Allergy, Asthma & Immunology 82.2 (1999): 185-191. Santaella, María L., Ivonne Font, and Orville M. Disdier. "Comparison of oral nicotinamide adenine dinucleotide (NADH) versus conventional therapy for chronic fatigue syndrome." Puerto Rico health sciences journal 23.2 (2004). Alegre, J., et al. "Nicotinamide adenine dinucleotide (NADH) in patients with chronic fatigue syndrome." Revista clinica espanola 210.6 (2010): 284-288.
L-tyrosine
L-tyrosine belongs to the semi-essential amino acids and can be synthesized from the essential amino acid L-phenylalanine during metabolism. In times of acute or chronic stress, L-tyrosine can increase performance and physical energy, also having a mood-lifting effect by increasing the noradrenaline level. If lower levels of L-phenylalanine are consumed, L-tyrosine becomes an essential amino acid and must be taken as a supplement. A deficiency of these amino acids can lead to reduced cognitive capability.

Scientific studies on L-tyrosine as an ingredient

Deijen, J. B., et al. "Tyrosine improves cognitive performance and reduces blood pressure in cadets after one week of a combat training course." Brain research bulletin 48.2 (1999): 203-209. Burgerstein, Uli P., Hugo Schurgast, and Michael B. Zimmermann. Handbuch Nährstoffe: Vorbeugen und heilen durch ausgewogene Ernährung. Georg Thieme Verlag, 2012. Krzyściak, Wirginia. "Activity of selected aromatic amino acids in biological systems." Acta Biochimica Polonica 58.4 (2011): 461-466.
L-arginine
As with L-tyrosine, L-arginine is one of the semi-essential amino acids as it can be produced from other amino acids and vitamins by the body. During times of sports activity, stress or during various diseases or periods of growth, the body's own production of the amino acid L-arginine is often not adequate and it needs to be taken as a supplement. L-arginine improves the supply of oxygen to the body, increases the blood circulation and boots endurance. L-arginine is also the precursor of creatinine, which is important for the energy metabolism of the muscles.

Scientific studies on L-arginine as an ingredient

Camic, Clayton L., et al. "Effects of arginine-based supplements on the physical working capacity at the fatigue threshold." The Journal of Strength & Conditioning Research 24.5 (2010): 1306-1312. Abel, Tilo, et al. "Influence of chronic supplementation of arginine aspartate in endurance athletes on performance and substrate metabolism." International journal of sports medicine 26.05 (2005): 344-349. Doutreleau, S., et al. "Chronic L-arginine supplementation enhances endurance exercise tolerance in heart failure patients." International journal of sports medicine 27.07 (2006): 567-572. McConell, Glenn K. "Effects of L-arginine supplementation on exercise metabolism." Current Opinion in Clinical Nutrition & Metabolic Care 10.1 (2007): 46-51.
Vitamin C
Vitamin C has a wide variety of positive effects on the body. Scientific studies have proven that people who take high levels of vitamin C are much better protected against respiratory infections. Like glutathione, vitamin C is one of the most important antioxidants for cleansing and strengthening the lungs from within.
Vitamin B5
Vitamin B5, also known as pantothenic acid, is not made by the body itself and must be consumed in our diet. As part of the coenzyme A (CoA), B5 plays a key role in the overall energy metabolism of the cells. Vitamin B5 helps the body to gain the optimum amount of energy from the food consumed, to form healthy cells, red blood cells, sexual and stress hormones. It boosts both mental and physical performance, while also reducing tiredness and fatigue symptoms.

Scientific studies on vitamin B5 as an ingredient

Depeint, Flore, et al. "Mitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolism." Chemico-biological interactions163.1 (2006): 94-112. Hamilton, Nathan D., and Benjamin V. Treadwell. "Nutritional supplement for increased energy and stamina." U.S. Patent No. 6,562,869. 13 May 2003. Martin, Robert WY, Simon A. Ogston, and John R. Evans. "Effects of vitamin and mineral supplementation on symptoms associated with chronic fatigue syndrome with Coxsackie B antibodies." Journal of nutritional medicine 4.1 (1994): 11-23.

Plants which influence our health and well-being can also have side effects. This page is designed to provide general information about these plants but is not intended as a guide for self-medication.