OPC plus
natural nutritional supplement for supportive treatment of Lyme disease


Nutritional supplement with high-quality ingredients for supportive treatment of Lyme disease

OPC plus is a natural nutritional supplement, with specially selected ingredients based on scientific studies. It can be used to support the treatment of Lyme disease.

Our nutritional supplement for supportive treatment of Lyme disease, OPC plus, contains the ingredients bromelain, grape seed, curcuma and resveratrol.


Bromelain is an enzyme found in the pineapple plant. It has become known for its anti-inflammatory and digestion-enhancing properties and is also used in the medical field to prevent swelling after injuries or operations. Its anti-thrombotic effect makes it an ideal choice for vein disorders and leg or pelvic vein thrombosis. Since bromelain can enhance the effectiveness of certain antibiotics, it is often given at the same time.

Scientific studies

Bhui, Kulpreet, et al. "Bromelain inhibits nuclear factor kappa‐B translocation, driving human epidermoid carcinoma A431 and melanoma A375 cells through G2/M arrest to apoptosis." Molecular carcinogenesis 51.3 (2012): 231-243.
Chobotova, Katya, Ann B. Vernallis, and Fadzilah Adibah Abdul Majid. "Bromelain’s activity and potential as an anti-cancer agent: current evidence and perspectives." Cancer letters 290.2 (2010): 148-156.
Bhui, Kulpreet, et al. "Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumor-initiation triggering mitochondrial death pathway." Cancer letters 282.2 (2009): 167-176.
Beuth, Josef. "Proteolytic enzyme therapy in evidence-based complementary oncology: fact or fiction?" Integrative cancer therapies 7.4 (2008): 311-316.
Secor, Eric R., et al. "Bromelain treatment reduces CD25 expression on activated CD4+ T cells in vitro." International immunopharmacology 9.3 (2009): 340-346.
Grape seed

Grape seeds contain a high polyphenol content and also OPC (oligomeric proanthocyanidins). Over recent years, grape seed extract and primarily the OPC in it has gained popularity as a secret anti-aging weapon. Numerous books have now been published on the subject. However, the extract is mainly known for its anti-oxidative and anti-inflammatory effects. Due to its potential proactive influence at a cellular level, OPC is now being discussed in connection with cancer research.

Scientific studies

Bagchi, Debasis, et al. "Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention." Toxicology 148.2 (2000): 187-197.

Jayaprakasha, G. K., Tamil Selvi, and K. K. Sakariah. "Antibacterial and antioxidant activities of grape (Vitis vinifera) seed extracts." Food research international 36.2 (2003): 117-122.

Al-Habib, Aamar, et al. "Bactericidal effect of grape seed extract on methicillin-resistant Staphylococcus aureus (MRSA)." The Journal of toxicological sciences 35.3 (2010): 357-364.

Baydar, Nilgün Göktürk, Gülcan Özkan, and Osman Sağdiç. "Total phenolic contents and antibacterial activities of grape (Vitis vinifera L.) extracts." Food Control 15.5 (2004): 335-339.

Jayaprakasha, G. K., R. P. Singh, and K. K. Sakariah. "Antioxidant activity of grape seed (Vitis vinifera) extracts on peroxidation models in vitro." Food chemistry 73.3 (2001): 285-290.

Curcuma – otherwise known as Indian saffron – is primarily known as a remedy in traditional Chinese and Indian medicine. This is due in particular to the ingredient curcumin. Many scientific studies have confirmed the efficacy of this natural substance in the treatment of inflammation. The anti-inflammatory effect is comparable to that of many well-known medicines on the market, without having their harmful side effects. Because curcumin is able to penetrate the blood-brain barrier, recent studies are also investigating whether it could potentially protect us from neurologically degenerative diseases. Other research is examining whether curcuma could be helpful in the treatment of cancer, lung disease or mercury poisoning.

Scientific studies

Singh, Rambir, et al. "Antibacterial activity of Curcuma longa rhizome extract on pathogenic bacteria." CURRENT SCIENCE-BANGALORE- 83.6 (2002): 737-740.
Araujo, C. A. C., and L. L. Leon. "Biological activities of Curcuma longa L."Memorias do Instituto Oswaldo Cruz 96.5 (2001): 723-728.
Çıkrıkçı, Simay, E. Mozioglu, and Hasibe Yılmaz. "Biological activity of curcuminoids isolated from Curcuma longa." Rec Nat Prod 2.1 (2008): 19-24.
Pundir, Ram Kumar, and Pranay Jain. "Comparative studies on the antimicrobial activity of black pepper (Piper nigrum) and turmeric (Curcuma longa) extracts." International Journal of Applied Biology and Pharmaceutical Technology 1.2 (2010): 492-500.
Packiavathy, Issac Abraham Sybiya Vasantha, et al. "Inhibition of biofilm development of uropathogens by curcumin–an anti-quorum sensing agent from Curcuma longa." Food chemistry 148 (2014): 453-460.
Resveratrol is frequently found in the skin of grapes and belongs to the so-called phytoalexins. These phytoalexins are formed by the plant as part of its immune system. Resveratrol has an antioxidative, anti-inflammatory and immune-modulating effect. It has recently gained popularity in the field of cancer research, where its potential values has already been proven in various scientific studies.

Scientific studies

Jang, Meishiang, et al. "Cancer chemopreventive activity of resveratrol, a natural product derived from grapes." Science 275.5297 (1997): 218-220.
Baur, Joseph A., and David A. Sinclair. "Therapeutic potential of resveratrol: the in vivo evidence." Nature reviews. Drug discovery 5.6 (2006): 493.
Shankar, Sharmila, Gyanendra Singh, and Rakesh K. Srivastava. "Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential." Frontiers in bioscience: a journal and virtual library 12 (2007): 4839-4854.
Aggarwal, Bharat B., et al. "Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies." Anticancer research 24.5A (2004): 2783-2840.
Das, Samarjit, and Dipak K. Das. "Anti-inflammatory responses of resveratrol." Inflammation & Allergy-Drug Targets (Formerly Current Drug Targets-Inflammation & Allergy) 6.3 (2007): 168-173.
Martín, Antonio Ramón, et al. "The effects of resveratrol, a phytoalexin derived from red wines, on chronic inflammation induced in an experimentally induced colitis model." British journal of pharmacology 147.8 (2006): 873-885.
Bereswill, Stefan, et al. "Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation." PloS one 5.12 (2010): e15099.

Plants which influence our health and well-being can also have side effects. This page is designed to provide general information about these plants but is not intended as a guide for self-medication.